Meet The Plastics – Regina, Gretchen and Karen. They rule North Shore High and will burn anyone who gets in their way. Home-schooled Cady Heron may think she knows a thing or two about survival of the fittest thanks to her zoologist parents, but high school is a whole new level of savage. When Cady devises a plan to end Regina's reign, she learns the hard way that you can't cross a queen bee without getting stung.