A little blob couple named Red and Orange are suddenly thrust into a world-altering pandemic. As the days of lockdown drag on, they work from home, do various quarantine activities to pass the time, and connect with friends and family virtually. They both end up being laid off from their jobs and months pass with them feeling listless. Orange gets a job that brings it back to the office, leaving Red home alone. As things steadily open up, Red remains inside, feeling increasingly isolated as other blobs return to their happy lives full of activities. Red's mental health continues to deteriorate as Orange tries to find ways to show Red love and support.